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  1. Acum 4 zile · Read the latest articles of The Lancet at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature.

  2. Acum 2 zile · First crystal structure of free fluvoxamine (FXM) maleate after the 40-year introduction. • Three FXM–H + are counter-balanced by three planar maleate − in the uncomplexed form (1).. Two FXM–H + B-rings enclosed in β-CD dimer are linked to the non-planar maleate 2− (2).. Unique host–guest recognition pattern of all the 2:2 β-CD–SSRI inclusion complexes.

  3. www.nature.comNature

    Acum 4 zile · First published in 1869, Nature is the world’s leading multidisciplinary science journal.

  4. www.science.org › journal › scienceScience | AAAS

    Acum 5 zile · Science is the leading multidisciplinary, international journal of peer-reviewed research including analysis and news coverage of breakthroughs and policy.

  5. Acum 10 ore · Plants exploit phenotypic plasticity to adapt their growth and development to prevailing environmental conditions. Interpretation of light and temperature signals are aided by the circadian system which provides a temporal context. Phenotypic plasticity provides a selective and competitive advantage in nature but is obstructive during large-scale, intensive agricultural practices since ...

  6. Acum 5 zile · Interestingly, we found that deletion of VPS21 or VPS9, encoding yeast Rab5 homologue Vps21p or the specific GEF Vps9p, impaired PM integrity during heat stress, although no PM integrity defect was evident at 25 o C ( Fig. 1 B-D). We also examined the requirement of Ypt53p, which is a stress-induced isoform of Vps21p ( 10, 11 ), but ypt53 Δ ...

  7. Acum 1 zi · Lyme borreliosis is the most common vector borne infectious disease in North America and Europe and both its incidence and the geographical range of endemic areas are increasing. 1–3 Lyme borreliosis is a systemic infectious disease that can affect multiple organ systems, causing a wide array of possible clinical manifestations. Although most patients respond well to appropriate antibiotic ...

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