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PLOS ONE welcomes original research submissions from the natural sciences, medical research, engineering, as well as the related social sciences and humanities, including: Primary research that contributes to the base of scientific knowledge, including interdisciplinary, replication studies, and negative or null results.
PLOS ONE considers original research articles from all disciplines within the journal’s scope in the natural sciences, medical research, engineering, as well as the related social sciences and humanities. The editors make decisions on submissions based on scientific rigor, regardless of novelty.
