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  1. The Protein database is a collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB. Protein sequences are the fundamental determinants of biological structure and function.

    • Clipboard

      The .gov means it's official. Federal government websites...

    • Protein Blast

      BlastP simply compares a protein query to a protein...

    • PMC Free Article Pmc441573

      Basic Local Alignment Search Tool (BLAST) is a sequence...

    • Blast

      The Basic Local Alignment Search Tool (BLAST) finds regions...

  2. BlastP simply compares a protein query to a protein database. PSI-BLAST allows the user to build a PSSM (position-specific scoring matrix) using the results of the first BlastP run. PHI-BLAST performs the search but limits alignments to those that match a pattern in the query.

  3. 1 iul. 2004 · Basic Local Alignment Search Tool (BLAST) is a sequence similarity search program that can be used via a web interface or as a stand-alone tool ( 1, 2 ). There are several types of BLAST to compare all combinations of nucleotide or protein queries with nucleotide or protein databases.

  4. 28 nov. 2023 · The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.

  5. 11 dec. 2023 · Abstract. Will protein structure search tools like AlphaFold replace protein sequence search with BLAST? We discuss the promises, using structure search for remote homology detection, and why protein BLAST, as the leading sequence search tool, should strive to incorporate structural information.

  6. 11 dec. 2023 · BLAST 1 is widely used in molecular biology to search for nucleotide and protein sequences. Three decades after BLAST was introduced, there were major breakthroughs in structure prediction,...

  7. The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between protein or nucleotide sequences. The program compares nucleotide or protein sequences to sequence in a database and calculates the statistical significance of the matches.

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