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  1. Recent in vivo imaging studies provide supportive evidence that periventricular white matter lesions are associated with cortical cholinergic deafferentation in elderly with leukoaraiosis. White matter lesions at the frontal horns, so-called “capping,” are in close proximity to cholinergic axons that originate in the basal forebrain.

  2. 21 mar. 2023 · There are several locations for white matter lesions. Those around the center black spaces are called "periventricular white matter lesions". Those located between the cortex and ventricles, with some space between, are just called "white matter lesions".

  3. 7 mar. 2024 · Periventricular-white matter hyperintensity (PV-WMH) is featured by gliosis, loosening of the WM, and loss around convoluted venules in perivascular spaces. In contrast, the primary characteristics of deep subcortical-white matter hypersensitivity (DS-WMH) are demyelination, gliosis, and augmented tissue loss as the lesions become serious.

  4. The white matter hyperintensity on T2w and FLAIR images are mostly present in the deep white matter, periventricular and juxtacortical region. Callosal and subcallosal region are rarely affected [Figure 19].

  5. White matter hyperintensities (WMH) are commonly seen on T2-weighted MRI and are often divided into 2 categories: periventricular WMH (PVWMH), which abut the cerebral ventricles, and deep WMH (DWMH), which are patchy areas of WMH in subcortical white matter distinct from the periventricular area. 1–8 Qualitative MRI studies evaluating the ...

  6. Periventricular white matter refers to white matter located immediately adjacent to the fluid-filled ventricles of the brain. Current Knowledge. Periventricular white matter is composed of bundles of myelinated nerve fibers (axons).

  7. 10 aug. 2022 · White matter hyperintensities (WMHs), characterized by bilateral and symmetrical hyperintensities on fluid-attenuated inversion-recovery imaging (FLAIR), are very common neuroradiological manifestations in the elderly (de Laat et al., 2011; Wardlaw et al., 2013; Graff-Radford et al., 2019 ).

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